||Image Analysis of Rat Breast Tissue
||Cascallana, Monika Agirre
||Ersbøll, Bjarne Kjær (DTU Data Analysis, Department of Informatics and Mathematical Modeling, Technical University of Denmark, DTU, DK-2800 Kgs. Lyngby, Denmark)
||Technical University of Denmark, DTU, DK-2800 Kgs. Lyngby, Denmark
||This thesis describes a method for automated analysis and feature extraction of mammary
gland structures of rats from 2D optical microscopy images of histological slides for evaluation of
effects of pesticides and for analysis of gland development.
The thesis is a product of project research carried due to a collaboration between Informatics
and Mathematical Modelling, DTU department, and the National Food Institute, DTU Food
The thesis is focused on evaluating the effects of pesticides in mammary glands, for
different groups of rats, which are characterized by age and gender, as well as evaluating the growth
and development with age.
Prior to evaluating the effects of the exposure and the development of the organ, the
mammary gland slides are used to implement an automatic method to extract features to the
posterior analysis. The extracted features are the area, density and branch and end-points quantity.
The result of this thesis is a user-friendly method which will be incorporated in other studies
at DTU Food. The developed method shows the lack of effect of the performed experiment, and the
develop of the mammary gland across the age and gender.
||Technical University of Denmark (DTU) : Kgs. Lyngby, Denmark
Creation date: 2010-02-25
Update date: 2010-10-28